Prescribing Pattern of Levetiracetam in Epilepsy Patients: A Cross-Sectional Study in a Tertiary Care Centre in Manipur

Objective: The objective is to shed light on the prescribing pattern of levetiracetam, a newer antiepileptic drug, in treatment different types epilepsy. Methods: A record-based cross-sectional study epilepsy patients who reported Therapeutic Drug Monitoring Unit Department Pharmacology, Regional Institute Medical Sciences, Manipur, was conducted. Case records receiving levetiracetam and reporting from January 2017 December 2020 were included. patient’s age, gender, weight; clinical diagnosis; dose; other co-administered AEDs all examined. Findings: Of 17 cases, majority adults, 52.9% males. patients’ average body weight (kg) 49.8  9.4. Generalised tonic-clonic seizures (GTCS) constituted cases (47.1%), followed by simple partial seizures, complex (23.5% each), absence (5.9%). 70.11% received LEV monotherapy, while remaining prescribed combination therapy. alone 87.5% GTCS cases. median daily dose 1000 mg (IQR-625). Novelty : observation that commonest type epilepsy, an eye-opener for another new monotherapy option GTCS. Keywords: Prescribing pattern; Levetiracetam; Antiepileptic; Epilepsy; Monotherapy